Evaluation of a high-throughput diagnostic system for detection of HIV-1 in dried blood spot samples from infants in Mozambique.

نویسندگان

  • Ilesh V Jani
  • Jennifer Sabatier
  • Adolfo Vubil
  • Shambavi Subbarao
  • Dulce Bila
  • Amina de Sousa
  • Nédio Mabunda
  • Albert Garcia
  • Beth Skaggs
  • Dennis Ellenberger
  • Artur Ramos
چکیده

We performed a comparative analysis between Roche Amplicor HIV-1 DNA test and CAPTAQ assay for the detection of HIV in 830 dried blood spot (DBS) pediatric samples collected in Mozambique. Our results demonstrated no statistical difference between these assays. The CAPTAQ assay approached nearly 100% repeatability/accuracy. The increased throughput of testing with minimal operator interference in performing the CAPTAQ assay clearly demonstrated that this method is an improvement over the Roche Amplicor HIV-1 DNA test, version 1.5.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 50 4  شماره 

صفحات  -

تاریخ انتشار 2012